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Compound
PGDB_C003397
6 activity records1 related patents
2D structure
C[C@H](NC(=O)Nc1ccc(CCOCCNCCS(C)(=O)=O)c(Cl)c1)c1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=OCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | > | 10000 | nM | - | — | IKZF3 | - | - | WO2026007898A1 | PGDB_A011249 | PGDB_C003397 | PGDB_AS002393 | View |
| DC50 | - | > | 10000 | nM | - | — | IKZF1 | - | - | WO2026007898A1 | PGDB_A029950 | PGDB_C003397 | PGDB_AS002166 | View |
| Selectivity index | IKZF3 | > | 245 | fold | - | — | - | - | - | WO2026007898A1 | PGDB_A034000 | PGDB_C003397 | PGDB_AS000375 | View |
| IC50 | - | = | 107 | nM | - | — | - | - | MDA-MB-453 | WO2026007898A1 | PGDB_A037465 | PGDB_C003397 | PGDB_AS002028 | View |
| DC50 | - | = | 40.8 | nM | - | — | GSPT1 | - | - | WO2026007898A1 | PGDB_A050155 | PGDB_C003397 | PGDB_AS002374 | View |
| Selectivity index | IKZF1 | > | 245 | fold | - | — | - | - | - | WO2026007898A1 | PGDB_A050485 | PGDB_C003397 | PGDB_AS001314 | View |