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Compound
PGDB_C003435
4 activity records1 related patents
2D structure
Cn1cc(-c2c(-c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)cnn2C)cc1C#NCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 75-90 | % | Concentration range: 10 uM | six hours | CSNK1A1 | - | HEK293 | EP4584259A1 | PGDB_A010055 | PGDB_C003435 | PGDB_AS000108 | View |
| DC50 | - | >= | 25 | nM | - | — | GSPT1 | - | HEK293 | EP4584259A1 | PGDB_A023440 | PGDB_C003435 | PGDB_AS001862 | View |
| DC50 | - | < | 25 | nM | - | — | CSNK1A1 | - | HEK293 | EP4584259A1 | PGDB_A035297 | PGDB_C003435 | PGDB_AS001103 | View |
| % Degradation | - | = | 0-25 | % | Concentration range: 10 uM | six hours | GSPT1 | - | HEK293 | EP4584259A1 | PGDB_A053731 | PGDB_C003435 | PGDB_AS001220 | View |