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Patent
EP4584259A1
731 compounds3,045 activity records6 assays
Patent summary
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | DC50 | - | < | 25 | nM | - | — | GSPT1 | - | HEK293 | PGDB_A007019 | PGDB_C003929 | PGDB_AS001862 | View |
 | % Degradation | - | = | 0-25 | % | Concentration range: 10 uM | six hours | GSPT1 | - | HEK293 | PGDB_A007066 | PGDB_C004143 | PGDB_AS001220 | View |
 | DC50 | - | < | 25 | nM | - | — | CSNK1A1 | - | HEK293 | PGDB_A007071 | PGDB_C004111 | PGDB_AS001103 | View |
 | % Degradation | - | = | 0-25 | % | Concentration range: 10 uM | six hours | GSPT1 | - | HEK293 | PGDB_A007094 | PGDB_C003899 | PGDB_AS001220 | View |
 | % Degradation | - | = | 25-75 | % | Concentration range: 10 uM | six hours | CSNK1A1 | - | HEK293 | PGDB_A007116 | PGDB_C004050 | PGDB_AS000108 | View |
 | DC50 | - | >= | 25 | nM | - | — | CSNK1A1 | - | HEK293 | PGDB_A007139 | PGDB_C003478 | PGDB_AS001103 | View |
 | DC50 | - | >= | 25 | nM | - | — | CSNK1A1 | - | HEK293 | PGDB_A007178 | PGDB_C004061 | PGDB_AS001103 | View |
 | % Degradation | - | = | 25-75 | % | Concentration range: 10 uM | six hours | CSNK1A1 | - | HEK293 | PGDB_A007181 | PGDB_C004012 | PGDB_AS000108 | View |
 | % Degradation | - | = | 90-100 | % | - | - | - | - | - | PGDB_A007200 | PGDB_C004063 | PGDB_AS001586 | View |
 | DC50 | - | >= | 25 | nM | - | — | GSPT1 | - | HEK293 | PGDB_A007214 | PGDB_C003698 | PGDB_AS001862 | View |
 | % Degradation | - | = | 25-75 | % | Concentration range: 10 uM | six hours | CSNK1A1 | - | HEK293 | PGDB_A007228 | PGDB_C003729 | PGDB_AS000108 | View |
 | DC50 | - | >= | 25 | nM | - | — | GSPT1 | - | HEK293 | PGDB_A007229 | PGDB_C003635 | PGDB_AS001862 | View |
 | DC50 | - | >= | 25 | nM | - | — | GSPT1 | - | HEK293 | PGDB_A007267 | PGDB_C003584 | PGDB_AS001862 | View |
 | DC50 | - | < | 25 | nM | - | — | CSNK1A1 | - | HEK293 | PGDB_A007337 | PGDB_C004057 | PGDB_AS001103 | View |
 | % Degradation | - | = | 0-25 | % | Concentration range: 10 uM | six hours | GSPT1 | - | HEK293 | PGDB_A007344 | PGDB_C003625 | PGDB_AS001220 | View |
 | DC50 | - | >= | 25 | nM | - | — | GSPT1 | - | HEK293 | PGDB_A007361 | PGDB_C003494 | PGDB_AS001862 | View |
 | DC50 | - | < | 25 | nM | - | — | CSNK1A1 | - | HEK293 | PGDB_A007389 | PGDB_C003692 | PGDB_AS001103 | View |
 | % Degradation | - | = | 25-75 | % | Concentration range: 10 uM | six hours | GSPT1 | - | HEK293 | PGDB_A007485 | PGDB_C003438 | PGDB_AS001220 | View |
 | % Degradation | - | = | 0-25 | % | Concentration range: 10 uM | six hours | GSPT1 | - | HEK293 | PGDB_A007525 | PGDB_C003564 | PGDB_AS001220 | View |
 | DC50 | - | < | 25 | nM | - | — | CSNK1A1 | - | HEK293 | PGDB_A007560 | PGDB_C003967 | PGDB_AS001103 | View |