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Compound
PGDB_C003727
6 activity records1 related patents
2D structure
COc1ccc(-c2c(-c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)cnn2C(F)F)c(Cl)c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | < | 25 | nM | - | — | GSPT1 | - | HEK293 | EP4584259A1 | PGDB_A009530 | PGDB_C003727 | PGDB_AS001862 | View |
| % Degradation | - | = | 0-25 | % | Concentration range: 10 uM | six hours | GSPT1 | - | HEK293 | EP4584259A1 | PGDB_A014843 | PGDB_C003727 | PGDB_AS001220 | View |
| % Degradation | - | = | 90-100 | % | - | - | - | - | - | EP4584259A1 | PGDB_A023863 | PGDB_C003727 | PGDB_AS001586 | View |
| DC50 | - | < | 25 | nM | - | — | CSNK1A1 | - | HEK293 | EP4584259A1 | PGDB_A027652 | PGDB_C003727 | PGDB_AS001103 | View |
| % Degradation | - | = | 90-100 | % | Concentration range: 10 uM | six hours | CSNK1A1 | - | HEK293 | EP4584259A1 | PGDB_A033775 | PGDB_C003727 | PGDB_AS000108 | View |
| EC50 | - | < | 100 | nM | - | — | - | - | - | EP4584259A1 | PGDB_A036920 | PGDB_C003727 | PGDB_AS002128 | View |