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Compound
PGDB_C003761
6 activity records1 related patents
2D structure
Cn1cnc(-c2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)c1-c1ccc(F)c(C#N)c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | >= | 25 | nM | - | — | GSPT1 | - | HEK293 | EP4584259A1 | PGDB_A017775 | PGDB_C003761 | PGDB_AS001862 | View |
| DC50 | - | < | 25 | nM | - | — | CSNK1A1 | - | HEK293 | EP4584259A1 | PGDB_A021117 | PGDB_C003761 | PGDB_AS001103 | View |
| % Degradation | - | = | 90-100 | % | - | - | - | - | - | EP4584259A1 | PGDB_A026289 | PGDB_C003761 | PGDB_AS001586 | View |
| % Degradation | - | = | 75-90 | % | Concentration range: 10 uM | six hours | CSNK1A1 | - | HEK293 | EP4584259A1 | PGDB_A027876 | PGDB_C003761 | PGDB_AS000108 | View |
| % Degradation | - | = | 90-100 | % | Concentration range: 10 uM | six hours | GSPT1 | - | HEK293 | EP4584259A1 | PGDB_A028888 | PGDB_C003761 | PGDB_AS001220 | View |
| EC50 | - | < | 100 | nM | - | — | - | - | - | EP4584259A1 | PGDB_A067564 | PGDB_C003761 | PGDB_AS002128 | View |