Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C005361
4 activity records1 related patents
2D structure
O=C1CCC(N2Cc3ccc(COC(=O)Nc4ccc(Cl)c(C#CC5CC5)c4)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 66.13 | % | Concentration context: 10 nM | 6 h | GSPT1 | - | NCI-H1155 | WO2024125437A1 | PGDB_A013042 | PGDB_C005361 | PGDB_AS000061 | View |
| % Degradation | - | = | 4.06 | % | Concentration context: 100 nM | 6 h | GSPT1 | - | NCI-H1155 | WO2024125437A1 | PGDB_A017380 | PGDB_C005361 | PGDB_AS001010 | View |
| IC50 | - | = | 5 | nM | - | — | - | - | NCI-H1155 | WO2024125437A1 | PGDB_A028516 | PGDB_C005361 | PGDB_AS001656 | View |
| IC50 | - | = | 203 | nM | - | — | CRBN | CRBN | - | WO2024125437A1 | PGDB_A051776 | PGDB_C005361 | PGDB_AS000407 | View |