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Compound
PGDB_C007544
4 activity records1 related patents
2D structure
N#Cc1ccc2c(c1)OC[C@H]1CN(Cc3ccc(Cc4ccc5c6c(cc(F)cc46)C(=O)N5C4CCC(=O)NC4=O)cn3)CCN21Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 91.8 | % | Concentration context: HiBiT IKZF1:_D max (%) | 20 h | IKZF1 | - | HT-1080 | EP4393915A1 | PGDB_A015647 | PGDB_C007544 | PGDB_AS001371 | View |
| Dmax | - | = | 53.2 | % | Concentration context: HiBiT SALL4:_D max (%) | 20 h | SALL4 | - | HT-1080 | EP4393915A1 | PGDB_A022168 | PGDB_C007544 | PGDB_AS001879 | View |
| DC50 | - | = | 0.4 | uM | - | — | SALL4 | - | HT-1080 | EP4393915A1 | PGDB_A043577 | PGDB_C007544 | PGDB_AS000384 | View |
| DC50 | - | = | 0.022 | nM | - | — | IKZF1 | - | HT-1080 | EP4393915A1 | PGDB_A052145 | PGDB_C007544 | PGDB_AS001653 | View |