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O=C1CCC(N2C(=O)c3cc(F)cc4c(Cc5ccc(CN6CCOCC6)cc5F)ccc2c34)C(=O)N1| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | > | 10 | uM | - | — | SALL4 | - | HT-1080 | EP4393915A1 | PGDB_A027627 | PGDB_C007550 | PGDB_AS000384 | View | |
| Dmax | - | = | 75.2 | % | Concentration context: HiBiT IKZF1:_D max (%) | 20 h | IKZF1 | - | HT-1080 | EP4393915A1 | PGDB_A034046 | PGDB_C007550 | PGDB_AS001371 | View | |
| Dmax | - | = | 34.9 | % | Concentration context: HiBiT SALL4:_D max (%) | 20 h | SALL4 | - | HT-1080 | EP4393915A1 | PGDB_A056533 | PGDB_C007550 | PGDB_AS001879 | View | |
| DC50 | - | = | 2.37 | nM | - | — | IKZF1 | - | HT-1080 | EP4393915A1 | PGDB_A067162 | PGDB_C007550 | PGDB_AS001653 | View |