Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C007557
4 activity records1 related patents
2D structure
CC(C)(C)N1CCN(Cc2ccc(Cc3ccc4c5c(cc(F)cc35)C(=O)N4C3CCC(=O)NC3=O)c(F)c2)CC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | > | 10 | uM | - | — | SALL4 | - | HT-1080 | EP4393915A1 | PGDB_A012437 | PGDB_C007557 | PGDB_AS000384 | View |
| DC50 | - | = | 1.22 | nM | - | — | IKZF1 | - | HT-1080 | EP4393915A1 | PGDB_A034183 | PGDB_C007557 | PGDB_AS001653 | View |
| Dmax | - | = | 87.3 | % | Concentration context: HiBiT IKZF1:_D max (%) | 20 h | IKZF1 | - | HT-1080 | EP4393915A1 | PGDB_A048633 | PGDB_C007557 | PGDB_AS001371 | View |
| Dmax | - | = | 49.1 | % | Concentration context: HiBiT SALL4:_D max (%) | 20 h | SALL4 | - | HT-1080 | EP4393915A1 | PGDB_A051115 | PGDB_C007557 | PGDB_AS001879 | View |