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Compound
PGDB_C008416
8 activity records1 related patents
2D structure
CCN[C@H]1CCCC[C@@H]1Cc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=OCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 0.261 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A007279 | PGDB_C008416 | PGDB_AS002086 | View |
| EC50 | - | = | 3.9 | nM | - | — | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A009919 | PGDB_C008416 | PGDB_AS002391 | View |
| Dmax | - | = | 94 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A030331 | PGDB_C008416 | PGDB_AS000211 | View |
| EC50 | - | = | 141 | nM | - | — | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A035968 | PGDB_C008416 | PGDB_AS001603 | View |
| Dmax | - | = | 83 | % | 10 uM | overnight | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A045534 | PGDB_C008416 | PGDB_AS002429 | View |
| EC50 | - | = | 0.029 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A051253 | PGDB_C008416 | PGDB_AS001535 | View |
| Fold change | DMSO control | = | 1.9 | fold | 10 uM | overnight | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A060452 | PGDB_C008416 | PGDB_AS002326 | View |
| Dmax | - | = | 31 | % | - | 24 h | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A065805 | PGDB_C008416 | PGDB_AS000216 | View |