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Compound
PGDB_C008516
11 activity records1 related patents
2D structure
CC(N[C@H]1CCCC[C@@H]1Cc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O)C1CC(F)(F)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 0.006 | uM | - | — | IKZF2 | - | - | JP2026020265A | PGDB_A012627 | PGDB_C008516 | PGDB_AS001524 | View |
| Dmax | - | = | 97 | % | - | 24 h | IKZF2 | - | - | JP2026020265A | PGDB_A014338 | PGDB_C008516 | PGDB_AS002581 | View |
| EC50 | - | = | 0.004 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A015896 | PGDB_C008516 | PGDB_AS001535 | View |
| Dmax | - | = | 97 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A021903 | PGDB_C008516 | PGDB_AS000211 | View |
| EC50 | - | > | 1 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A035813 | PGDB_C008516 | PGDB_AS002086 | View |
| Dmax | - | = | 97 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A046570 | PGDB_C008516 | PGDB_AS000211 | View |
| EC50 | - | = | 0.002 | uM | - | — | IKZF2 | - | - | JP2026020265A | PGDB_A050618 | PGDB_C008516 | PGDB_AS001524 | View |
| Dmax | - | = | 99 | % | - | 24 h | IKZF2 | - | - | JP2026020265A | PGDB_A056495 | PGDB_C008516 | PGDB_AS002581 | View |
| EC50 | - | = | 0.054 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A067668 | PGDB_C008516 | PGDB_AS002086 | View |
| EC50 | - | = | 0.001 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A073680 | PGDB_C008516 | PGDB_AS001535 | View |
| Dmax | - | = | 34 | % | - | 24 h | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A077771 | PGDB_C008516 | PGDB_AS000216 | View |