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Compound
PGDB_C008518
10 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(C[C@H]4CCCC[C@@H]4NC4CC5CC5C4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 0.004 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A008543 | PGDB_C008518 | PGDB_AS001535 | View |
| Dmax | - | = | 43 | % | - | 24 h | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A014663 | PGDB_C008518 | PGDB_AS000216 | View |
| EC50 | - | = | 0.035 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A015274 | PGDB_C008518 | PGDB_AS002086 | View |
| Dmax | - | = | 32 | % | - | 24 h | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A025795 | PGDB_C008518 | PGDB_AS000216 | View |
| Dmax | - | = | 97 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A029552 | PGDB_C008518 | PGDB_AS000211 | View |
| EC50 | - | = | 0.006 | uM | - | — | IKZF2 | - | - | JP2026020265A | PGDB_A038467 | PGDB_C008518 | PGDB_AS001524 | View |
| EC50 | - | = | 0.001 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A052539 | PGDB_C008518 | PGDB_AS001535 | View |
| EC50 | - | = | 0.055 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A054396 | PGDB_C008518 | PGDB_AS002086 | View |
| Dmax | - | = | 98 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A065244 | PGDB_C008518 | PGDB_AS000211 | View |
| Dmax | - | = | 98 | % | - | 24 h | IKZF2 | - | - | JP2026020265A | PGDB_A069879 | PGDB_C008518 | PGDB_AS002581 | View |