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Compound
PGDB_C008524
10 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(C[C@H]4CCCC[C@@H]4NC4CCC(OC(F)(F)F)CC4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 44 | % | - | 24 h | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A008657 | PGDB_C008524 | PGDB_AS000216 | View |
| EC50 | - | = | 0.002 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A028815 | PGDB_C008524 | PGDB_AS001535 | View |
| EC50 | - | = | 0.004 | uM | - | — | IKZF2 | - | - | JP2026020265A | PGDB_A030638 | PGDB_C008524 | PGDB_AS001524 | View |
| Dmax | - | = | 100 | % | - | 24 h | IKZF2 | - | - | JP2026020265A | PGDB_A033160 | PGDB_C008524 | PGDB_AS002581 | View |
| EC50 | - | = | 0.055 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A036771 | PGDB_C008524 | PGDB_AS002086 | View |
| Dmax | - | = | 34 | % | - | 24 h | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A039363 | PGDB_C008524 | PGDB_AS000216 | View |
| EC50 | - | = | 0.168 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A039463 | PGDB_C008524 | PGDB_AS002086 | View |
| Dmax | - | = | 96 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A043315 | PGDB_C008524 | PGDB_AS000211 | View |
| Dmax | - | = | 95 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A054281 | PGDB_C008524 | PGDB_AS000211 | View |
| EC50 | - | = | 0.002 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A058329 | PGDB_C008524 | PGDB_AS001535 | View |