Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C008586
10 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(C[C@H]4CCCC[C@@H]4NC4CCC(C(F)F)CC4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 98 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A008000 | PGDB_C008586 | PGDB_AS000211 | View |
| EC50 | - | = | 0.003 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A011810 | PGDB_C008586 | PGDB_AS001535 | View |
| EC50 | - | = | 0.051 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A015777 | PGDB_C008586 | PGDB_AS002086 | View |
| EC50 | - | = | 0.085 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A015854 | PGDB_C008586 | PGDB_AS002086 | View |
| Dmax | - | = | 89 | % | - | 24 h | IKZF2 | - | - | JP2026020265A | PGDB_A030371 | PGDB_C008586 | PGDB_AS002581 | View |
| Dmax | - | = | 34 | % | - | 24 h | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A045121 | PGDB_C008586 | PGDB_AS000216 | View |
| Dmax | - | = | 97 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A046432 | PGDB_C008586 | PGDB_AS000211 | View |
| Dmax | - | = | 44 | % | - | 24 h | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A053761 | PGDB_C008586 | PGDB_AS000216 | View |
| EC50 | - | = | 0.002 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A072994 | PGDB_C008586 | PGDB_AS001535 | View |
| EC50 | - | = | 0.002 | uM | - | — | IKZF2 | - | - | JP2026020265A | PGDB_A073353 | PGDB_C008586 | PGDB_AS001524 | View |