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Compound
PGDB_C008615
10 activity records1 related patents
2D structure
O=C1CCC(N2Cc3c(ccc(C[C@H]4CCCC[C@@H]4NC4CCCC4)c3F)C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 0.032 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A008509 | PGDB_C008615 | PGDB_AS001535 | View |
| EC50 | - | = | 0.002 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A019448 | PGDB_C008615 | PGDB_AS001535 | View |
| % Degradation | - | = | 0.5 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A023793 | PGDB_C008615 | PGDB_AS000906 | View |
| Dmax | - | = | 39 | % | - | 24 h | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A027233 | PGDB_C008615 | PGDB_AS000216 | View |
| Dmax | - | = | 87 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A041139 | PGDB_C008615 | PGDB_AS000211 | View |
| Dmax | - | = | 98 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A048322 | PGDB_C008615 | PGDB_AS000211 | View |
| EC50 | - | = | 0.003 | uM | - | — | IKZF2 | - | - | JP2026020265A | PGDB_A052879 | PGDB_C008615 | PGDB_AS001524 | View |
| EC50 | - | > | 1 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A053663 | PGDB_C008615 | PGDB_AS002086 | View |
| EC50 | - | = | 0.062 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A056860 | PGDB_C008615 | PGDB_AS002086 | View |
| Dmax | - | = | 95 | % | - | 24 h | IKZF2 | - | - | JP2026020265A | PGDB_A076348 | PGDB_C008615 | PGDB_AS002581 | View |