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Compound
PGDB_C008630
11 activity records1 related patents
2D structure
O=C1CCC(N2Cc3c(ccc(C[C@H]4OCCC[C@@H]4NC4CCC(C(F)F)CC4)c3F)C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 96 | % | - | 24 h | IKZF2 | - | - | JP2026020265A | PGDB_A014470 | PGDB_C008630 | PGDB_AS002581 | View |
| EC50 | - | > | 10 | uM | - | — | SALL4 | - | HEK293 | JP2026020265A | PGDB_A016256 | PGDB_C008630 | PGDB_AS001573 | View |
| Dmax | - | = | 26 | % | - | 24 h | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A028690 | PGDB_C008630 | PGDB_AS000216 | View |
| EC50 | - | > | 1 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A031745 | PGDB_C008630 | PGDB_AS002086 | View |
| Dmax | - | = | 98 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A035475 | PGDB_C008630 | PGDB_AS000211 | View |
| Dmax | - | = | 95 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A042800 | PGDB_C008630 | PGDB_AS000211 | View |
| EC50 | - | = | 0.092 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A044204 | PGDB_C008630 | PGDB_AS002086 | View |
| EC50 | - | = | 0.004 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A045460 | PGDB_C008630 | PGDB_AS001535 | View |
| EC50 | - | = | 0.005 | uM | - | — | IKZF2 | - | - | JP2026020265A | PGDB_A048753 | PGDB_C008630 | PGDB_AS001524 | View |
| EC50 | - | = | 0.007 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A056793 | PGDB_C008630 | PGDB_AS001535 | View |
| % Degradation | - | = | 0.34 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A068250 | PGDB_C008630 | PGDB_AS000906 | View |