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Compound
PGDB_C008635
10 activity records1 related patents
2D structure
CC(N[C@H]1CCCO[C@@H]1Cc1ccc2c(c1F)CN(C1CCC(=O)NC1=O)C2=O)C1CCOCC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 0.055 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A010210 | PGDB_C008635 | PGDB_AS001535 | View |
| EC50 | - | = | 0.005 | uM | - | — | IKZF2 | - | - | JP2026020265A | PGDB_A013724 | PGDB_C008635 | PGDB_AS001524 | View |
| % Degradation | - | = | 0.31 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A022378 | PGDB_C008635 | PGDB_AS000906 | View |
| Dmax | - | = | 76 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A044603 | PGDB_C008635 | PGDB_AS000211 | View |
| Dmax | - | = | 94 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A047156 | PGDB_C008635 | PGDB_AS000211 | View |
| EC50 | - | > | 1 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A058611 | PGDB_C008635 | PGDB_AS002086 | View |
| EC50 | - | = | 0.01 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A058831 | PGDB_C008635 | PGDB_AS001535 | View |
| EC50 | - | > | 1 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A070046 | PGDB_C008635 | PGDB_AS002086 | View |
| EC50 | - | > | 10 | uM | - | — | SALL4 | - | HEK293 | JP2026020265A | PGDB_A072802 | PGDB_C008635 | PGDB_AS001573 | View |
| Dmax | - | = | 96 | % | - | 24 h | IKZF2 | - | - | JP2026020265A | PGDB_A077010 | PGDB_C008635 | PGDB_AS002581 | View |