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Compound
PGDB_C008722
11 activity records1 related patents
2D structure
O=C1CCC(N2Cc3c(ccc(C[C@H]4CCCC[C@@H]4NC4CCCCC4)c3F)C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 2 | nM | - | — | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A026773 | PGDB_C008722 | PGDB_AS002391 | View |
| Dmax | - | = | 88 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A034458 | PGDB_C008722 | PGDB_AS000211 | View |
| EC50 | - | = | 0.026 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A038411 | PGDB_C008722 | PGDB_AS001535 | View |
| Dmax | - | = | 88 | % | 10 uM | overnight | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A046103 | PGDB_C008722 | PGDB_AS002429 | View |
| Dmax | - | = | 99 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A046794 | PGDB_C008722 | PGDB_AS000211 | View |
| EC50 | - | = | 0.101 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A050239 | PGDB_C008722 | PGDB_AS002086 | View |
| EC50 | - | > | 1 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A066409 | PGDB_C008722 | PGDB_AS002086 | View |
| EC50 | - | = | 0.001 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A069149 | PGDB_C008722 | PGDB_AS001535 | View |
| Fold change | DMSO control | = | 2.1 | fold | 10 uM | overnight | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A070072 | PGDB_C008722 | PGDB_AS002326 | View |
| Dmax | - | = | 38 | % | - | 24 h | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A071982 | PGDB_C008722 | PGDB_AS000216 | View |
| EC50 | - | = | 2.3 | nM | - | — | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A077110 | PGDB_C008722 | PGDB_AS001603 | View |