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Compound
PGDB_C008723
8 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(C[C@H]4CCCC[C@@H]4NCCc4ccccc4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 0.023 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A015397 | PGDB_C008723 | PGDB_AS001535 | View |
| Dmax | - | = | 91 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A020384 | PGDB_C008723 | PGDB_AS000211 | View |
| Fold change | DMSO control | = | 2.2 | fold | 10 uM | overnight | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A027340 | PGDB_C008723 | PGDB_AS002326 | View |
| EC50 | - | = | 0.8 | nM | - | — | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A030873 | PGDB_C008723 | PGDB_AS002391 | View |
| EC50 | - | = | 8 | nM | - | — | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A032050 | PGDB_C008723 | PGDB_AS001603 | View |
| EC50 | - | = | 0.039 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A038535 | PGDB_C008723 | PGDB_AS002086 | View |
| Dmax | - | = | 22 | % | - | 24 h | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A041412 | PGDB_C008723 | PGDB_AS000216 | View |
| Dmax | - | = | 93 | % | 10 uM | overnight | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A063963 | PGDB_C008723 | PGDB_AS002429 | View |