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Compound
PGDB_C008728
7 activity records1 related patents
2D structure
C[C@@H](N[C@H]1CCCC[C@@H]1Cc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O)c1ccccc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 95 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A014710 | PGDB_C008728 | PGDB_AS000211 | View |
| EC50 | - | = | 0.023 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A015275 | PGDB_C008728 | PGDB_AS001535 | View |
| EC50 | - | = | 7.5 | nM | - | — | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A023010 | PGDB_C008728 | PGDB_AS002391 | View |
| EC50 | - | > | 1 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A026488 | PGDB_C008728 | PGDB_AS002086 | View |
| EC50 | - | = | 10 | nM | - | — | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A056634 | PGDB_C008728 | PGDB_AS001603 | View |
| Fold change | DMSO control | = | 1.6 | fold | 10 uM | overnight | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A058079 | PGDB_C008728 | PGDB_AS002326 | View |
| Dmax | - | = | 61 | % | 10 uM | overnight | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A063143 | PGDB_C008728 | PGDB_AS002429 | View |