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Compound
PGDB_C008729
7 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(C[C@H]4CCCC[C@@H]4NCC45CCC(CC4)C5)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 18 | nM | - | — | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A008327 | PGDB_C008729 | PGDB_AS001603 | View |
| EC50 | - | = | 0.037 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A036174 | PGDB_C008729 | PGDB_AS001535 | View |
| Dmax | - | = | 92 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A036370 | PGDB_C008729 | PGDB_AS000211 | View |
| EC50 | - | = | 6.1 | nM | - | — | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A051039 | PGDB_C008729 | PGDB_AS002391 | View |
| EC50 | - | > | 1 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A054309 | PGDB_C008729 | PGDB_AS002086 | View |
| Dmax | - | = | 83 | % | 10 uM | overnight | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A061585 | PGDB_C008729 | PGDB_AS002429 | View |
| Fold change | DMSO control | = | 1.8 | fold | 10 uM | overnight | IKZF2 | - | Jurkat | JP2026020265A | PGDB_A066030 | PGDB_C008729 | PGDB_AS002326 | View |