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Compound
PGDB_C011104
6 activity records1 related patents
2D structure
O=C1CC[C@H](N2Cc3cc(O[C@H]4CCN(Cc5cc(F)c6nc(N7C[C@H]8CCO[C@H]8C7)ncc6c5)C4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 0.366 | uM | - | — | WEE1 | - | MDA-MB-231 | WO2025137053A1 | PGDB_A014860 | PGDB_C011104 | PGDB_AS001832 | View |
| Ymin | - | = | 32.4 | % | Concentration series: 1 uM, 10 uM | 4 h | WEE1 | - | 293T-LentiXWEE1-ePL | WO2025137053A1 | PGDB_A016891 | PGDB_C011104 | PGDB_AS001848 | View |
| EC50 | - | = | 0.011 | uM | - | — | WEE1 | - | MKN45 | WO2025137053A1 | PGDB_A035776 | PGDB_C011104 | PGDB_AS002043 | View |
| EC50 | - | = | 0.006 | uM | - | — | WEE1 | - | 293T-LentiXWEE1-ePL | WO2025137053A1 | PGDB_A040937 | PGDB_C011104 | PGDB_AS001798 | View |
| Ymin | - | = | 45.1 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MDA-MB-231 | WO2025137053A1 | PGDB_A054585 | PGDB_C011104 | PGDB_AS002525 | View |
| Ymin | - | = | 11.7 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | WO2025137053A1 | PGDB_A066483 | PGDB_C011104 | PGDB_AS000997 | View |