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Compound
PGDB_C011111
6 activity records1 related patents
2D structure
COC[C@@H]1CN(Cc2ccc3nc(N4C[C@@H]5O[C@@H]5C4)ccc3c2)C[C@H]1Oc1ccc2c(c1)CN([C@H]1CCC(=O)NC1=O)C2=OCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ymin | - | = | 43.7 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MDA-MB-231 | WO2025137053A1 | PGDB_A009608 | PGDB_C011111 | PGDB_AS002525 | View |
| EC50 | - | = | 0.002 | uM | - | — | WEE1 | - | MKN45 | WO2025137053A1 | PGDB_A017476 | PGDB_C011111 | PGDB_AS002043 | View |
| Ymin | - | = | 10.8 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | WO2025137053A1 | PGDB_A019253 | PGDB_C011111 | PGDB_AS000997 | View |
| EC50 | - | = | 0.048 | uM | - | — | WEE1 | - | MDA-MB-231 | WO2025137053A1 | PGDB_A040047 | PGDB_C011111 | PGDB_AS001832 | View |
| EC50 | - | = | 0 | uM | - | — | WEE1 | - | 293T-LentiXWEE1-ePL | WO2025137053A1 | PGDB_A040684 | PGDB_C011111 | PGDB_AS001798 | View |
| Ymin | - | = | 29.6 | % | Concentration series: 1 uM, 10 uM | 4 h | WEE1 | - | 293T-LentiXWEE1-ePL | WO2025137053A1 | PGDB_A049534 | PGDB_C011111 | PGDB_AS001848 | View |