Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C011121
6 activity records1 related patents
2D structure
O=C1CC[C@@H](N2C(=O)c3ccc(O[C@H]4CCN(Cc5cc(F)c6nc(C7CCOCC7)ccc6c5)C4)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 0.039 | uM | - | — | WEE1 | - | MKN45 | WO2025137053A1 | PGDB_A018812 | PGDB_C011121 | PGDB_AS002043 | View |
| Ymin | - | = | 32.8 | % | Concentration series: 1 uM, 10 uM | 4 h | WEE1 | - | 293T-LentiXWEE1-ePL | WO2025137053A1 | PGDB_A019393 | PGDB_C011121 | PGDB_AS001848 | View |
| Ymin | - | = | 53.8 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MDA-MB-231 | WO2025137053A1 | PGDB_A035511 | PGDB_C011121 | PGDB_AS002525 | View |
| EC50 | - | = | 0.999 | uM | - | — | WEE1 | - | MDA-MB-231 | WO2025137053A1 | PGDB_A052157 | PGDB_C011121 | PGDB_AS001832 | View |
| Ymin | - | = | 12.3 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | WO2025137053A1 | PGDB_A066113 | PGDB_C011121 | PGDB_AS000997 | View |
| EC50 | - | = | 0.008 | uM | - | — | WEE1 | - | 293T-LentiXWEE1-ePL | WO2025137053A1 | PGDB_A070321 | PGDB_C011121 | PGDB_AS001798 | View |