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Compound
PGDB_C011176
6 activity records1 related patents
2D structure
O=C1CC[C@H](N2Cc3cc(O[C@H]4CCN(Cc5cc(F)c6nc(N7C[C@@H]8CCO[C@@H]8C7)ccc6c5)C4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 0.026 | uM | - | — | WEE1 | - | MDA-MB-231 | WO2025137053A1 | PGDB_A012247 | PGDB_C011176 | PGDB_AS001832 | View |
| EC50 | - | = | 0.002 | uM | - | — | WEE1 | - | MKN45 | WO2025137053A1 | PGDB_A037651 | PGDB_C011176 | PGDB_AS002043 | View |
| EC50 | - | = | 0.002 | uM | - | — | WEE1 | - | 293T-LentiXWEE1-ePL | WO2025137053A1 | PGDB_A044506 | PGDB_C011176 | PGDB_AS001798 | View |
| Ymin | - | = | 9 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | WO2025137053A1 | PGDB_A047787 | PGDB_C011176 | PGDB_AS000997 | View |
| Ymin | - | = | 17.9 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MDA-MB-231 | WO2025137053A1 | PGDB_A052996 | PGDB_C011176 | PGDB_AS002525 | View |
| Ymin | - | = | 27.5 | % | Concentration series: 1 uM, 10 uM | 4 h | WEE1 | - | 293T-LentiXWEE1-ePL | WO2025137053A1 | PGDB_A073312 | PGDB_C011176 | PGDB_AS001848 | View |