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Compound
PGDB_C011222
6 activity records1 related patents
2D structure
Cc1cc([C@@H]2CN(Cc3cc(F)c4nc(C5CCOCC5)ccc4c3)C[C@H]2Oc2ccc3c(c2)CN([C@H]2CCC(=O)NC2=O)C3=O)cc(C)n1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ymin | - | = | 30.5 | % | Concentration series: 1 uM, 10 uM | 4 h | WEE1 | - | 293T-LentiXWEE1-ePL | WO2025137053A1 | PGDB_A010457 | PGDB_C011222 | PGDB_AS001848 | View |
| EC50 | - | = | 0.001 | uM | - | — | WEE1 | - | 293T-LentiXWEE1-ePL | WO2025137053A1 | PGDB_A027491 | PGDB_C011222 | PGDB_AS001798 | View |
| EC50 | - | = | 0.127 | uM | - | — | WEE1 | - | MDA-MB-231 | WO2025137053A1 | PGDB_A028426 | PGDB_C011222 | PGDB_AS001832 | View |
| EC50 | - | = | 0.011 | uM | - | — | WEE1 | - | MKN45 | WO2025137053A1 | PGDB_A042264 | PGDB_C011222 | PGDB_AS002043 | View |
| Ymin | - | = | 83.3 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MDA-MB-231 | WO2025137053A1 | PGDB_A060998 | PGDB_C011222 | PGDB_AS002525 | View |
| Ymin | - | = | 18.2 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | WO2025137053A1 | PGDB_A069610 | PGDB_C011222 | PGDB_AS000997 | View |