Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C011242
6 activity records1 related patents
2D structure
Cc1cc([C@H]2CN(Cc3cc(F)c4nc(C5CCOCC5)ccc4c3)C[C@@H]2Oc2ccc3c(c2)CN([C@H]2CCC(=O)NC2=O)C3=O)cc(C)n1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 0.003 | uM | - | — | WEE1 | - | MKN45 | WO2025137053A1 | PGDB_A016458 | PGDB_C011242 | PGDB_AS002043 | View |
| EC50 | - | = | 0.001 | uM | - | — | WEE1 | - | 293T-LentiXWEE1-ePL | WO2025137053A1 | PGDB_A033387 | PGDB_C011242 | PGDB_AS001798 | View |
| Ymin | - | = | 74.8 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MDA-MB-231 | WO2025137053A1 | PGDB_A038861 | PGDB_C011242 | PGDB_AS002525 | View |
| Ymin | - | = | 28.4 | % | Concentration series: 1 uM, 10 uM | 4 h | WEE1 | - | 293T-LentiXWEE1-ePL | WO2025137053A1 | PGDB_A041752 | PGDB_C011242 | PGDB_AS001848 | View |
| EC50 | - | = | 0.207 | uM | - | — | WEE1 | - | MDA-MB-231 | WO2025137053A1 | PGDB_A047304 | PGDB_C011242 | PGDB_AS001832 | View |
| Ymin | - | = | 9.9 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | WO2025137053A1 | PGDB_A068127 | PGDB_C011242 | PGDB_AS000997 | View |