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Compound
PGDB_C014211
7 activity records1 related patents
2D structure
Cc1ccc(Sc2ccccc2N2CCN(Cc3ccc4c(c3)CN(N3CCC(=O)NC3=O)C4=O)CC2)c(C)c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | < | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | WO2024245444A1 | PGDB_A007566 | PGDB_C014211 | PGDB_AS000339 | View |
| IC50 | - | = | 1000-5000 | nM | - | — | - | - | MM.1S | WO2024245444A1 | PGDB_A015061 | PGDB_C014211 | PGDB_AS001978 | View |
| % Degradation | - | < | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | WO2024245444A1 | PGDB_A024186 | PGDB_C014211 | PGDB_AS001444 | View |
| % Degradation | - | < | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | WO2024245444A1 | PGDB_A038239 | PGDB_C014211 | PGDB_AS001967 | View |
| % Degradation | - | < | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | - | - | WO2024245444A1 | PGDB_A059296 | PGDB_C014211 | PGDB_AS002298 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | - | - | WO2024245444A1 | PGDB_A072699 | PGDB_C014211 | PGDB_AS000969 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | - | - | WO2024245444A1 | PGDB_A075076 | PGDB_C014211 | PGDB_AS001137 | View |