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Compound
PGDB_C014303
8 activity records1 related patents
2D structure
O=C1CCN(N2Cc3cc(CN4CCN(c5nc(Cl)nc6c5SCC6)CC4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | < | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | - | - | WO2024245444A1 | PGDB_A016835 | PGDB_C014303 | PGDB_AS002298 | View |
| % Inhibition | - | = | 20-40 | % | 10 nM | - | - | - | H292 | WO2024245444A1 | PGDB_A025683 | PGDB_C014303 | PGDB_AS001605 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | WO2024245444A1 | PGDB_A031118 | PGDB_C014303 | PGDB_AS001444 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | WO2024245444A1 | PGDB_A053132 | PGDB_C014303 | PGDB_AS001967 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | - | - | WO2024245444A1 | PGDB_A055559 | PGDB_C014303 | PGDB_AS001137 | View |
| % Inhibition | - | = | 20-40 | % | 500 nM | - | - | - | H292 | WO2024245444A1 | PGDB_A066942 | PGDB_C014303 | PGDB_AS000415 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | - | - | WO2024245444A1 | PGDB_A071834 | PGDB_C014303 | PGDB_AS000969 | View |
| % Degradation | - | < | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | WO2024245444A1 | PGDB_A075386 | PGDB_C014303 | PGDB_AS000339 | View |