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O=C1CCN(N2C(=O)c3ccc(CN4CC=C(c5ccnc(Cl)c5Cl)CC4)cc3C2=O)C(=O)N1| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | < | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | - | - | WO2024245444A1 | PGDB_A010203 | PGDB_C020117 | PGDB_AS002298 | View | |
| % Degradation | - | < | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | WO2024245444A1 | PGDB_A017064 | PGDB_C020117 | PGDB_AS001967 | View | |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | WO2024245444A1 | PGDB_A020264 | PGDB_C020117 | PGDB_AS000339 | View | |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | WO2024245444A1 | PGDB_A020809 | PGDB_C020117 | PGDB_AS001444 | View | |
| % Degradation | - | < | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | - | - | WO2024245444A1 | PGDB_A059963 | PGDB_C020117 | PGDB_AS000969 | View | |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | - | - | WO2024245444A1 | PGDB_A074454 | PGDB_C020117 | PGDB_AS001137 | View |