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Compound
PGDB_C024267
8 activity records1 related patents
2D structure
O=C1CCC(N2C(=O)c3ccc(NN4CCN(Cc5ccc(-c6ccc(Cl)cc6)cc5)CC4)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | WO2025162225A1 | PGDB_A010085 | PGDB_C024267 | PGDB_AS000689 | View |
| IC50 | - | > | 500 | nM | - | — | - | - | TMD8 | WO2025162225A1 | PGDB_A014246 | PGDB_C024267 | PGDB_AS000863 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | WO2025162225A1 | PGDB_A027377 | PGDB_C024267 | PGDB_AS000351 | View |
| % Inhibition | - | > | 30 | % | 1 uM | - | IKZF3 | - | - | WO2025162225A1 | PGDB_A031061 | PGDB_C024267 | PGDB_AS001982 | View |
| % Degradation | - | = | 20-100 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | CRBN | - | WO2025162225A1 | PGDB_A040333 | PGDB_C024267 | PGDB_AS000750 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | CRBN | - | WO2025162225A1 | PGDB_A050320 | PGDB_C024267 | PGDB_AS001726 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | CRBN | - | WO2025162225A1 | PGDB_A069643 | PGDB_C024267 | PGDB_AS002453 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | WO2025162225A1 | PGDB_A074735 | PGDB_C024267 | PGDB_AS000091 | View |