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Compound
PGDB_C024272
7 activity records1 related patents
2D structure
CC(C)(C)OC(=O)N1CCC(c2ccc(Cl)cc2)=C(CN2CCN(Nc3ccc4c(c3)C(=O)N(C3CCC(=O)NC3=O)C4=O)CC2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 20-100 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | CRBN | - | WO2025162225A1 | PGDB_A011954 | PGDB_C024272 | PGDB_AS001726 | View |
| % Degradation | - | = | 20-100 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | WO2025162225A1 | PGDB_A034818 | PGDB_C024272 | PGDB_AS000091 | View |
| % Degradation | - | = | 20-100 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | CRBN | - | WO2025162225A1 | PGDB_A047603 | PGDB_C024272 | PGDB_AS002453 | View |
| % Degradation | - | = | 20-100 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | CRBN | - | WO2025162225A1 | PGDB_A058189 | PGDB_C024272 | PGDB_AS000750 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | WO2025162225A1 | PGDB_A060260 | PGDB_C024272 | PGDB_AS000351 | View |
| % Degradation | - | = | 20-100 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | WO2025162225A1 | PGDB_A070220 | PGDB_C024272 | PGDB_AS000689 | View |
| IC50 | - | > | 10 | nM | - | — | - | - | MV-4-11 | WO2025162225A1 | PGDB_A071092 | PGDB_C024272 | PGDB_AS001804 | View |