Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C024274
6 activity records1 related patents
2D structure
CC(C)Cc1ccc([C@H](C)C(=O)N2CCN(Nc3ccc4c(c3F)CN(C3CCC(=O)NC3=O)C4=O)CC2)cc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | WO2025162225A1 | PGDB_A009644 | PGDB_C024274 | PGDB_AS000689 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | CRBN | - | WO2025162225A1 | PGDB_A031425 | PGDB_C024274 | PGDB_AS002453 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | CRBN | - | WO2025162225A1 | PGDB_A043096 | PGDB_C024274 | PGDB_AS001726 | View |
| % Degradation | - | = | 20-100 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | CRBN | - | WO2025162225A1 | PGDB_A050089 | PGDB_C024274 | PGDB_AS000750 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | WO2025162225A1 | PGDB_A059445 | PGDB_C024274 | PGDB_AS000091 | View |
| % Degradation | - | = | 20-100 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | WO2025162225A1 | PGDB_A062842 | PGDB_C024274 | PGDB_AS000351 | View |