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O=C1CCC(N2C(=O)c3cc(F)c(NN4CCN(CC5=C(c6ccc(F)cc6)CCCC5)CC4)cc3C2=O)C(=O)N1| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | WO2025162225A1 | PGDB_A011394 | PGDB_C024292 | PGDB_AS000689 | View | |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | WO2025162225A1 | PGDB_A039307 | PGDB_C024292 | PGDB_AS000351 | View | |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | CRBN | - | WO2025162225A1 | PGDB_A047511 | PGDB_C024292 | PGDB_AS002453 | View | |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | CRBN | - | WO2025162225A1 | PGDB_A047758 | PGDB_C024292 | PGDB_AS000750 | View | |
| % Degradation | - | = | 20-100 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | CRBN | - | WO2025162225A1 | PGDB_A049107 | PGDB_C024292 | PGDB_AS001726 | View | |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | WO2025162225A1 | PGDB_A076562 | PGDB_C024292 | PGDB_AS000091 | View |