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Compound
PGDB_C024309
7 activity records1 related patents
2D structure
CC1(C)CCC(/C=N/N2CCN(c3ccc4c(c3)C(=O)N(C3CCC(=O)NC3=O)C4=O)CC2)=C(c2ccc(Cl)cc2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | CRBN | - | WO2025162225A1 | PGDB_A025833 | PGDB_C024309 | PGDB_AS000750 | View |
| % Degradation | - | = | 20-100 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | WO2025162225A1 | PGDB_A037255 | PGDB_C024309 | PGDB_AS000351 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | WO2025162225A1 | PGDB_A044834 | PGDB_C024309 | PGDB_AS000689 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | WO2025162225A1 | PGDB_A051838 | PGDB_C024309 | PGDB_AS000091 | View |
| % Degradation | - | = | 20-100 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | CRBN | - | WO2025162225A1 | PGDB_A066689 | PGDB_C024309 | PGDB_AS001726 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | CRBN | - | WO2025162225A1 | PGDB_A071787 | PGDB_C024309 | PGDB_AS002453 | View |
| % Inhibition | - | = | 20-30 | % | 0.1 uM | - | IKZF3 | - | - | WO2025162225A1 | PGDB_A073543 | PGDB_C024309 | PGDB_AS001671 | View |