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Compound
PGDB_C024413
6 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(NN4CCN(CC5=C(c6ccc(F)cc6)CCOC5)CC4)cc(F)c3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | CRBN | - | WO2025162225A1 | PGDB_A012909 | PGDB_C024413 | PGDB_AS002453 | View |
| % Degradation | - | = | 20-100 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | CRBN | - | WO2025162225A1 | PGDB_A015523 | PGDB_C024413 | PGDB_AS001726 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | WO2025162225A1 | PGDB_A049694 | PGDB_C024413 | PGDB_AS000689 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | WO2025162225A1 | PGDB_A050343 | PGDB_C024413 | PGDB_AS000351 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | WO2025162225A1 | PGDB_A054211 | PGDB_C024413 | PGDB_AS000091 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | CRBN | - | WO2025162225A1 | PGDB_A066333 | PGDB_C024413 | PGDB_AS000750 | View |