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Compound
PGDB_C026739
11 activity records2 related patents
2D structure
O=C(O)[C@H]1CCCC[C@H]1C(=O)N1CC2c3ccc(CN4C(=O)c5ccccc5S4=O)cc3OC21Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 64 | % | - | 24 h | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A007515 | PGDB_C026739 | PGDB_AS000211 | View |
| IC50 | - | = | 8 | uM | - | — | - | - | - | WO2021178355A1 | PGDB_A009833 | PGDB_C026739 | PGDB_AS001041 | View |
| IC50 | - | = | 3 | uM | - | — | - | - | - | WO2021178355A1 | PGDB_A016582 | PGDB_C026739 | PGDB_AS001041 | View |
| IC50 | - | = | 69.7 | uM | - | — | - | - | - | WO2021178355A1 | PGDB_A029481 | PGDB_C026739 | PGDB_AS001041 | View |
| IC50 | - | = | 2.3 | uM | - | — | - | - | - | WO2021178355A1 | PGDB_A035215 | PGDB_C026739 | PGDB_AS001041 | View |
| IC50 | - | = | 3 | uM | - | — | - | - | - | WO2021178355A1 | PGDB_A042174 | PGDB_C026739 | PGDB_AS001041 | View |
| IC50 | - | = | 20.8 | uM | - | — | - | - | - | WO2021178355A1 | PGDB_A049538 | PGDB_C026739 | PGDB_AS001041 | View |
| EC50 | - | > | 50 | uM | - | — | IKZF1 | - | HEK293 | JP2026020265A | PGDB_A053740 | PGDB_C026739 | PGDB_AS002086 | View |
| IC50 | - | = | 8 | uM | - | — | - | - | - | WO2021178355A1 | PGDB_A058040 | PGDB_C026739 | PGDB_AS001041 | View |
| EC50 | - | = | 0.159 | uM | - | — | IKZF2 | - | HEK293 | JP2026020265A | PGDB_A066883 | PGDB_C026739 | PGDB_AS001535 | View |
| IC50 | - | = | 2.2 | uM | - | — | - | - | - | WO2021178355A1 | PGDB_A076646 | PGDB_C026739 | PGDB_AS001041 | View |