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C[C@H]1CC2(CCN(c3ccc(C(=O)N4CCC(O[C@H]5CC[C@H](CN6CCN7c8ccc(N9CCC(=O)NC9=O)cc8OCC[C@H]7C6)CC5)CC4)cc3)CC2)CN1c1ccc(C#N)c(C(F)(F)F)c1| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 75 | % | 50 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A000046 | PGDB_C029766 | PGDB_AS001838 | View | |
| % Degradation | - | = | 35 | % | 5 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A003195 | PGDB_C029766 | PGDB_AS001354 | View | |
| % Degradation | - | = | 59 | % | 100 nM | - | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A079415 | PGDB_C029766 | PGDB_AS002389 | View | |
| IC50 | - | = | 0.095 | nM | - | — | AR | - | VCaP | WO2026061104A1 | PGDB_A080454 | PGDB_C029766 | PGDB_AS000271 | View |