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Compound
PGDB_C030302
9 activity records1 related patents
2D structure
Nc1nnc(-c2cc(F)ccc2O)cc1N1CC2CCC(C1)N2c1cccc(CN2CCN(Cc3cccc4c3CN(C3CCC(=O)NC3=O)C4=O)CC2)c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | <= | 1 | nM | - | — | - | - | H838 | WO2026061475A1 | PGDB_A001440 | PGDB_C030302 | PGDB_AS000282 | View |
| IC50 | - | = | 200-500 | nM | - | — | - | - | A375 | WO2026061475A1 | PGDB_A002271 | PGDB_C030302 | PGDB_AS002441 | View |
| IC50 | - | = | 700-900 | nM | - | — | - | - | CFPAC-1 | WO2026061475A1 | PGDB_A006988 | PGDB_C030302 | PGDB_AS000179 | View |
| IC50 | - | = | 200-500 | nM | - | — | - | - | H2126 | WO2026061475A1 | PGDB_A077936 | PGDB_C030302 | PGDB_AS001417 | View |
| IC50 | - | = | 200-500 | nM | - | — | - | - | H1944 | WO2026061475A1 | PGDB_A078585 | PGDB_C030302 | PGDB_AS001924 | View |
| % Degradation | - | <= | 50 | % | Concentration series: 500 nM, 50 nM | - | SMARCA2 | - | MV-4-11 | WO2026061475A1 | PGDB_A081198 | PGDB_C030302 | PGDB_AS002335 | View |
| % Degradation | - | <= | 50 | % | Concentration series: 500 nM, 50 nM | - | SMARCA4 | - | MV-4-11 | WO2026061475A1 | PGDB_A081637 | PGDB_C030302 | PGDB_AS002340 | View |