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Compound
PGDB_C032424
8 activity records1 related patents
2D structure
COCCN(C(=O)[C@H]1[C@@H]2CC[C@H]1CN(c1cnnc(-c3ccccc3O)c1)C2)C1CCN(CCC2CCN(c3ccc([C@H]4CCC(=O)NC4=O)c(F)c3)CC2)CC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 5.85 | nM | - | — | SMARCA2 | - | Calu-6 | WO2026128580A1 | PGDB_A000963 | PGDB_C032424 | PGDB_AS002506 | View |
| DC50 | - | = | 6.37 | nM | - | — | SMARCA2 | - | Calu-6 | WO2026128580A1 | PGDB_A002825 | PGDB_C032424 | PGDB_AS002506 | View |
| Dmax | - | = | 17.75 | % | - | 5 min | SMARCA4 | - | Calu-6 | WO2026128580A1 | PGDB_A005401 | PGDB_C032424 | PGDB_AS002111 | View |
| DC50 | - | = | 1000 | nM | - | — | SMARCA4 | - | Calu-6 | WO2026128580A1 | PGDB_A006661 | PGDB_C032424 | PGDB_AS001413 | View |
| Dmax | - | = | 90.22 | % | - | - | SMARCA2 | - | Calu-6 | WO2026128580A1 | PGDB_A080885 | PGDB_C032424 | PGDB_AS002073 | View |
| Dmax | - | = | 85.81 | % | - | - | SMARCA2 | - | Calu-6 | WO2026128580A1 | PGDB_A081112 | PGDB_C032424 | PGDB_AS002073 | View |
| Dmax | - | = | 15.13 | % | - | 5 min | SMARCA4 | - | Calu-6 | WO2026128580A1 | PGDB_A081165 | PGDB_C032424 | PGDB_AS002111 | View |
| DC50 | - | = | 1000 | nM | - | — | SMARCA4 | - | Calu-6 | WO2026128580A1 | PGDB_A081471 | PGDB_C032424 | PGDB_AS001413 | View |