PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberAU2021359129A1

AssigneeProxygen

TitleHeterocyclic cullin ring ubiquitin ligase compounds and uses thereof

Family ID72964476

Family members10

Filing year2021

Publication date2023-06-01

JurisdictionAU

Compounds77

Activity records297

Assays7

Activity compounds and values

Activity records

297 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
DC50	-	>	10	uM	-	—	CCNK	-	-	PGDB_A007396	PGDB_C019114	PGDB_AS000583	View
EC50	-	<=	0.25	uM	-	—	-	-	KBM7	PGDB_A007794	PGDB_C019085	PGDB_AS000333	View
LC50	-	=	5.682	uM	-	—	-	-	KBM7	PGDB_A007968	PGDB_C019080	PGDB_AS001722	View
LC50	-	=	1.812	uM	-	—	-	-	KBM7	PGDB_A008354	PGDB_C019076	PGDB_AS002507	View
EC50	-	=	0.5-1	uM	-	—	CCNK	-	KBM7	PGDB_A008519	PGDB_C019083	PGDB_AS001877	View
DC50	-	>	10	uM	-	—	CCNK	-	-	PGDB_A008599	PGDB_C019094	PGDB_AS000583	View
DC50	-	=	0.1-0.5	uM	-	—	CCNK	-	-	PGDB_A008614	PGDB_C019082	PGDB_AS000583	View
DC50	-	=	0.1-0.5	uM	-	—	CCNK	-	-	PGDB_A008757	PGDB_C019125	PGDB_AS000583	View
DC50	-	<=	0.1	uM	-	—	CCNK	-	-	PGDB_A009666	PGDB_C019145	PGDB_AS000583	View
EC50	-	>	10	uM	-	—	CCNK	-	KBM7	PGDB_A009737	PGDB_C019122	PGDB_AS001877	View
EC50	-	=	1-10	uM	-	—	CCNK	-	-	PGDB_A010237	PGDB_C019112	PGDB_AS000733	View
DC50	-	>	10	uM	-	—	CCNK	-	-	PGDB_A010272	PGDB_C019118	PGDB_AS000583	View
DC50	-	>	10	uM	-	—	CCNK	-	-	PGDB_A010502	PGDB_C019101	PGDB_AS000583	View
DC50	-	>	10	uM	-	—	CCNK	-	-	PGDB_A010825	PGDB_C019084	PGDB_AS000583	View
DC50	-	=	0.1-0.5	uM	-	—	CCNK	-	-	PGDB_A011016	PGDB_C019134	PGDB_AS000583	View
EC50	-	=	1-10	uM	-	—	CCNK	-	-	PGDB_A011506	PGDB_C019139	PGDB_AS000733	View
EC50	-	=	0.5-1	uM	-	—	CCNK	-	-	PGDB_A011649	PGDB_C019123	PGDB_AS000733	View
DC50	-	<=	0.1	uM	-	—	CCNK	-	-	PGDB_A012082	PGDB_C019143	PGDB_AS000583	View
EC50	-	>	10	uM	-	—	CCNK	-	KBM7	PGDB_A012092	PGDB_C019127	PGDB_AS001877	View
EC50	-	=	1-10	uM	-	—	CCNK	-	-	PGDB_A012463	PGDB_C019136	PGDB_AS000733	View

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