PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberCN117982498A

AssigneeSuzhou Kintor Pharmaceuticals

TitleA composition containing a protein degrading agent or inhibitor and its use

Family ID90892510

Family members1

Filing year2023

Publication date2024-05-07

JurisdictionCN

Compounds117

Activity records204

Assays5

Activity compounds and values

Activity records

204 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
% Degradation	-	=	54	%	10 nM	-	-	-	HL-60	PGDB_A007054	PGDB_C000641	PGDB_AS001270	View
IC50	-	=	10	nM	-	—	-	-	HL-60	PGDB_A008255	PGDB_C000546	PGDB_AS001350	View
% Degradation	-	=	48	%	10 nM	-	-	-	HL-60	PGDB_A008811	PGDB_C000589	PGDB_AS001270	View
IC50	-	=	0.6	nM	-	—	-	-	HL-60	PGDB_A009479	PGDB_C000621	PGDB_AS001350	View
IC50	-	<	0.2	nM	-	—	-	-	HL-60	PGDB_A010598	PGDB_C000585	PGDB_AS001350	View
IC50	-	=	60	nM	-	—	-	-	HL-60	PGDB_A010766	PGDB_C000553	PGDB_AS001350	View
IC50	-	=	0.3	nM	-	—	-	-	HL-60	PGDB_A010948	PGDB_C000554	PGDB_AS001350	View
IC50	-	=	0.1	nM	-	—	-	-	HL-60	PGDB_A011509	PGDB_C000628	PGDB_AS001350	View
IC50	-	<	0.2	nM	-	—	-	-	HL-60	PGDB_A011708	PGDB_C000598	PGDB_AS001350	View
% Degradation	-	=	95	%	10 nM	24 h	-	-	HL-60	PGDB_A011941	PGDB_C000556	PGDB_AS001212	View
% Degradation	-	=	84	%	10 nM	-	-	-	HL-60	PGDB_A012239	PGDB_C000607	PGDB_AS001270	View
IC50	-	=	1	nM	-	—	-	-	HL-60	PGDB_A012284	PGDB_C000619	PGDB_AS001350	View
% Degradation	-	=	100	%	10 nM	-	-	-	HL-60	PGDB_A012673	PGDB_C000636	PGDB_AS001270	View
IC50	-	=	14	nM	-	—	-	-	HL-60	PGDB_A012924	PGDB_C000549	PGDB_AS001350	View
IC50	-	<	0.2	nM	-	—	-	-	HL-60	PGDB_A013460	PGDB_C000650	PGDB_AS001350	View
% Degradation	-	=	100	%	10 nM	24 h	-	-	HL-60	PGDB_A014243	PGDB_C000615	PGDB_AS001212	View
% Degradation	-	=	90	%	10 nM	-	-	-	HL-60	PGDB_A014536	PGDB_C000604	PGDB_AS001270	View
% Degradation	-	=	100	%	10 nM	-	-	-	HL-60	PGDB_A014879	PGDB_C000556	PGDB_AS001270	View
% Degradation	-	=	75	%	10 nM	24 h	-	-	HL-60	PGDB_A014956	PGDB_C000559	PGDB_AS001212	View
IC50	-	=	55	nM	-	—	-	-	HL-60	PGDB_A015184	PGDB_C000639	PGDB_AS001350	View

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