PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

25 activity records

Assay familyviability

Systemcell_based

ReadoutIC50

E3Not specified

Cell lineMDA-MB-468

Detection target% Cell viability

Activity compounds and values

Activity records

25 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
IC50	-	=	21.45	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A009502	PGDB_C007266	PGDB_AS000658	View
IC50	-	=	0.03	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A010315	PGDB_C007253	PGDB_AS000658	View
IC50	-	=	3.103	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A010568	PGDB_C007246	PGDB_AS000658	View
IC50	-	=	18.7	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A012874	PGDB_C007258	PGDB_AS000658	View
IC50	-	=	27.28	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A016153	PGDB_C007256	PGDB_AS000658	View
IC50	-	=	44.5	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A023174	PGDB_C007306	PGDB_AS000658	View
IC50	-	=	7.667	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A024414	PGDB_C007251	PGDB_AS000658	View
IC50	-	=	40.22	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A026429	PGDB_C007297	PGDB_AS000658	View
IC50	-	=	2.43	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A032377	PGDB_C007247	PGDB_AS000658	View
IC50	-	=	4.3	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A042099	PGDB_C007324	PGDB_AS000658	View
IC50	-	=	80.71	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A042903	PGDB_C007304	PGDB_AS000658	View
IC50	-	=	15.68	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A044847	PGDB_C007286	PGDB_AS000658	View
IC50	-	=	122.9	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A045340	PGDB_C007273	PGDB_AS000658	View
IC50	-	=	6.599	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A046976	PGDB_C007279	PGDB_AS000658	View
IC50	-	=	477.6	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A050516	PGDB_C007271	PGDB_AS000658	View
IC50	-	=	25.9	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A053131	PGDB_C007267	PGDB_AS000658	View
IC50	-	=	14.94	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A053163	PGDB_C007299	PGDB_AS000658	View
IC50	-	=	82.05	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A058673	PGDB_C007285	PGDB_AS000658	View
IC50	-	=	18.33	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A058889	PGDB_C007268	PGDB_AS000658	View
IC50	-	=	1.65	nM	-	—	CDK12	-	MDA-MB-468	CN120590389A	PGDB_A061080	PGDB_C007244	PGDB_AS000658	View

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