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Compound
PGDB_C009245
6 activity records3 related patents
2D structure
O=C1CCC(c2cccc(-c3ccc(-n4ccccc4=O)s3)c2Cl)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 90.8 | % | 0.02 nM | - | VAV1 | - | - | WO2026119120A1 | PGDB_A000255 | PGDB_C009245 | PGDB_AS000657 | View |
| DC50 | - | = | 5.9 | nM | - | — | VAV1 | - | - | WO2026119120A1 | PGDB_A000433 | PGDB_C009245 | PGDB_AS001984 | View |
| IC50 | - | <= | 1 | nM | - | — | VAV1 | - | primaryT | WO2026114368A1 | PGDB_A003766 | PGDB_C009245 | PGDB_AS001463 | View |
| IC50 | - | <= | 1 | nM | - | — | VAV1 | - | primaryT | WO2026114368A1 | PGDB_A005398 | PGDB_C009245 | PGDB_AS000300 | View |
| Dmax | - | = | 98.1 | % | Concentration series: 1000 nM, 250 nM, 62.5 nM, 15.6 nM, 3.9 nM, 0.98 nM, 0.24 nM, 0 nM | 24 h | VAV1 | - | Jurkat | WO2026041143A1 | PGDB_A014016 | PGDB_C009245 | PGDB_AS000206 | View |
| DC50 | - | <= | 10 | nM | - | — | VAV1 | - | Jurkat | WO2026041143A1 | PGDB_A039440 | PGDB_C009245 | PGDB_AS001882 | View |