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Compound
PGDB_C002739
4 activity records1 related patents
2D structure
CC1(C)CCC(CN2CCN(Cc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C(C(F)(F)F)C2)=C(c2ccc(F)cc2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 0.94 | uM | - | — | CRBN | CRBN | - | WO2024032689A1 | PGDB_A007902 | PGDB_C002739 | PGDB_AS000095 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | GSPT1 | - | - | WO2024032689A1 | PGDB_A045148 | PGDB_C002739 | PGDB_AS000668 | View |
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | IKZF3 | - | - | WO2024032689A1 | PGDB_A063855 | PGDB_C002739 | PGDB_AS000176 | View |
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | IKZF1 | - | - | WO2024032689A1 | PGDB_A066719 | PGDB_C002739 | PGDB_AS002239 | View |