Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C002555
5 activity records1 related patents
2D structure
CC1(C)CCC(C(=O)N2CCC3(CC2)CN(Cc2ccc4c(c2)CN(C2CCC(=O)NC2=O)C4=O)C3)=C(c2ccc(Cl)cc2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 0.7 | uM | - | — | CRBN | CRBN | - | WO2024032689A1 | PGDB_A010900 | PGDB_C002555 | PGDB_AS000095 | View |
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | GSPT1 | - | - | WO2024032689A1 | PGDB_A033200 | PGDB_C002555 | PGDB_AS000668 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | IKZF3 | - | - | WO2024032689A1 | PGDB_A036845 | PGDB_C002555 | PGDB_AS000176 | View |
| IC50 | - | = | 100-500 | nM | - | — | - | - | MM.1S | WO2024032689A1 | PGDB_A050892 | PGDB_C002555 | PGDB_AS001703 | View |
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | IKZF1 | - | - | WO2024032689A1 | PGDB_A067259 | PGDB_C002555 | PGDB_AS002239 | View |