Assay

PGDB_AS000225

System: cell_basedTarget: VAV1Cell line: REC-1
Assay context summary

Assay context

16 activity records
Assay family% Degradation
Systemcell_based
ReadoutDC50
TargetVAV1
E3Not specified
Cell lineREC-1
OrganismHomo sapiens
Activity compounds and values

Activity records

16 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C031400
DC50-=0.49nM-—VAV1-REC-1WO2026103798A1PGDB_A000837PGDB_C031400PGDB_AS000225View
2D structure for PGDB_C031341
DC50-=4.3nM-—VAV1-REC-1WO2026103798A1PGDB_A001628PGDB_C031341PGDB_AS000225View
2D structure for PGDB_C031359
DC50-=2.13nM-—VAV1-REC-1WO2026103798A1PGDB_A001910PGDB_C031359PGDB_AS000225View
2D structure for PGDB_C031372
DC50-=0.36nM-—VAV1-REC-1WO2026103798A1PGDB_A002140PGDB_C031372PGDB_AS000225View
2D structure for PGDB_C031362
DC50-=2.23nM-—VAV1-REC-1WO2026103798A1PGDB_A002258PGDB_C031362PGDB_AS000225View
2D structure for PGDB_C031356
DC50-=0.81nM-—VAV1-REC-1WO2026103798A1PGDB_A002494PGDB_C031356PGDB_AS000225View
2D structure for PGDB_C031377
DC50-=0.32nM-—VAV1-REC-1WO2026103798A1PGDB_A002917PGDB_C031377PGDB_AS000225View
2D structure for PGDB_C031366
DC50-=19.55nM-—VAV1-REC-1WO2026103798A1PGDB_A005778PGDB_C031366PGDB_AS000225View
2D structure for PGDB_C031396
DC50-=1.17nM-—VAV1-REC-1WO2026103798A1PGDB_A006399PGDB_C031396PGDB_AS000225View
2D structure for PGDB_C031401
DC50-=0.95nM-—VAV1-REC-1WO2026103798A1PGDB_A006489PGDB_C031401PGDB_AS000225View
2D structure for PGDB_C031399
DC50-=104.95nM-—VAV1-REC-1WO2026103798A1PGDB_A077982PGDB_C031399PGDB_AS000225View
2D structure for PGDB_C031368
DC50-=0.7nM-—VAV1-REC-1WO2026103798A1PGDB_A078906PGDB_C031368PGDB_AS000225View
2D structure for PGDB_C031337
DC50-=10.67nM-—VAV1-REC-1WO2026103798A1PGDB_A079316PGDB_C031337PGDB_AS000225View
2D structure for PGDB_C031364
DC50-=11.2nM-—VAV1-REC-1WO2026103798A1PGDB_A079622PGDB_C031364PGDB_AS000225View
2D structure for PGDB_C031363
DC50-=2.97nM-—VAV1-REC-1WO2026103798A1PGDB_A080641PGDB_C031363PGDB_AS000225View
2D structure for PGDB_C031336
DC50-=1.93nM-—VAV1-REC-1WO2026103798A1PGDB_A081211PGDB_C031336PGDB_AS000225View
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