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Compound
PGDB_C019027
4 activity records1 related patents
2D structure
Cn1cnc2c(C(=O)NC3CCC(=O)NC3=O)cccc21Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | <= | 25 | % | 20 uM | 24 h | IKZF1 | CRBN | NCI-H929 | AU2020392427A1 | PGDB_A018685 | PGDB_C019027 | PGDB_AS000227 | View |
| % Degradation | - | <= | 25 | % | 20 uM | 24 h | CSNK1A1 | - | NCI-H929 | AU2020392427A1 | PGDB_A029315 | PGDB_C019027 | PGDB_AS000343 | View |
| % Degradation | - | <= | 25 | % | 20 uM | 24 h | SALL4 | - | NCI-H929 | AU2020392427A1 | PGDB_A059039 | PGDB_C019027 | PGDB_AS002409 | View |
| Ki | - | = | 1-10 | uM | - | — | CRBN | CRBN | - | AU2020392427A1 | PGDB_A063196 | PGDB_C019027 | PGDB_AS000153 | View |