PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

66 activity records

Assay family% Degradation

Systemcell_based

Readout% Degradation

TargetGSPT1

E3Not specified

Cell lineJeKo-1

TechnologyWestern_blot

Detection targetprotein_degradation

Activity compounds and values

Activity records

66 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	=	56	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A008510	PGDB_C005320	PGDB_AS000305	View
% Degradation	-	=	95	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A009617	PGDB_C005331	PGDB_AS000305	View
% Degradation	-	=	97	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A009651	PGDB_C005311	PGDB_AS000305	View
% Degradation	-	=	95.6	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A012097	PGDB_C005329	PGDB_AS000305	View
% Degradation	-	=	97	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A015727	PGDB_C005302	PGDB_AS000305	View
% Degradation	-	=	80	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A016595	PGDB_C005340	PGDB_AS000305	View
% Degradation	-	=	77	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A016833	PGDB_C005313	PGDB_AS000305	View
% Degradation	-	=	93.7	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A017379	PGDB_C005318	PGDB_AS000305	View
% Degradation	-	=	93	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A017712	PGDB_C005307	PGDB_AS000305	View
% Degradation	-	=	99	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A022134	PGDB_C005304	PGDB_AS000305	View
% Degradation	-	=	94	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A022627	PGDB_C005345	PGDB_AS000305	View
% Degradation	-	=	92.7	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A023125	PGDB_C005341	PGDB_AS000305	View
% Degradation	-	=	88	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A024920	PGDB_C005336	PGDB_AS000305	View
% Degradation	-	=	100	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A025093	PGDB_C005328	PGDB_AS000305	View
% Degradation	-	=	95	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A025266	PGDB_C005353	PGDB_AS000305	View
% Degradation	-	=	93.6	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A026855	PGDB_C005350	PGDB_AS000305	View
% Degradation	-	=	85.8	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A026886	PGDB_C005347	PGDB_AS000305	View
% Degradation	-	=	98.7	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A028759	PGDB_C005309	PGDB_AS000305	View
% Degradation	-	=	93	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A031826	PGDB_C005314	PGDB_AS000305	View
% Degradation	-	=	93	%	10 uM	24 h	GSPT1	-	JeKo-1	WO2023078410A1	PGDB_A031882	PGDB_C005344	PGDB_AS000305	View

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