Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C005329
5 activity records1 related patents
2D structure
CC(C)(C)OC(=O)N[C@H](C(=O)NCc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O)c1ccccc1ClCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 95.6 | % | 10 uM | 24 h | GSPT1 | - | JeKo-1 | WO2023078410A1 | PGDB_A012097 | PGDB_C005329 | PGDB_AS000305 | View |
| % Degradation | - | = | 94.2 | % | 100 nM | 24 h | GSPT1 | - | JeKo-1 | WO2023078410A1 | PGDB_A031224 | PGDB_C005329 | PGDB_AS002119 | View |
| IC50 | - | = | 3.2 | nM | - | — | GSPT1 | - | HNT-34 | WO2023078410A1 | PGDB_A033979 | PGDB_C005329 | PGDB_AS000001 | View |
| IC50 | - | = | 4.2 | nM | - | — | GSPT1 | - | HL-60 | WO2023078410A1 | PGDB_A056470 | PGDB_C005329 | PGDB_AS002047 | View |
| IC50 | - | = | 0.1 | nM | - | — | GSPT1 | - | JeKo-1 | WO2023078410A1 | PGDB_A065581 | PGDB_C005329 | PGDB_AS001490 | View |